AppSurgeOn - Neurosimulator Vol.I is the first 3D neurosurgical simulator for mobile. It offers an impactful 3D educational experience of cognitive neurosurgical training characterized by full interactivity, high realism and impressive accuracy. This first volume is focused on basic frontal and temporal approaches.

Neurosimulator revolutionizes the neurosurgical training allowing to simulate a preoperative decision-making and a realistic intracranial exploration on a virtual patient. The UpSurgeOn Team, made by neurosurgeons and digital artists, uses the most powerful 3D technology and a strong 3D modeling process to reproduce an interactive surgical field.

AppSurgeOn - Neurosimulator Vol.I is organized into two simulation modes: ROI mode and Craniotomy mode. Each mode is organized into specific steps reproducing a realistic neurosurgical simulation of step-by-step decision-making to perform frontal and temporal craniotomies.
ROI mode is a 6-step simulation setup that begins with the selection of a ROI (Region Of Interest) from a list of 15 ROIs. In the next steps, the system leads you to select a suitable craniotomy from a list of 9 frontal/temporal approaches, and matches these two variables to calculate the best patient positioning for that specific approach. After a 3D real time simulation of the surgical approach, you can experience an interactive microsurgical exploration by using a virtual microscope and deforming the brain tissue in order to access the selected ROI. This innovative process is designed to empower the understanding of the microsurgical perspectives and the surgical ergonomics.
Craniotomy is a 4-step procedure which considers specifically the surgical approaches and the patient positioning.

The UpSurgeOn Team is made by neurosurgeons that are engaged with clinical practice every day. The contents of the simulations were produced through a novel process of “scientific 3D modeling”, created by UpSurgeOn. It consists of a systematic 3D reproduction of human neuroanatomy validated through a continue intraoperative validation.

- Full overview of 15 ROI (Region Of Interest) from a complete head MRI and an interactive 3D model of the patient head.
- Angiography-like visualization of vascular ROIs.
- Selection of right/left procedure.
- 3D overview of 9 frontal/temporal craniotomies.
- Fully 3D interactivity (rotation, zoom and pan).
- Selection of a correct patient position on the operating table.
- Patient head positioning (rotation, flexion-extension, lateral tilt).
- Fixation of the patient head with the Mayfield Head Holder.
- 3D animations of 9 frontal/temporal approaches, from skin incision to dura opening.
- Fully 3D interactive brain retraction.
- Intracranial exploration through a surgical microscope.
- Intracranial neuroanatomical labels.
- Wide texts concerning indications, techniques, landmarks, red flags and surgical notes from scientific literature.
- 3D simulation of the closure steps for each approach
- HD button for high resolution textures and anti-aliasing (for wide screen projection).

What’s New

Version 1.3

Starting from April 2018 UpSurgeOn is supported by WFNS (World Federation of Neurosurgical Societies).
Now 3D Skull Atlas hosts an official section dedicated to WFNS-YNF (Young Neurosurgeons Forum) activities.

Ratings and Reviews

5.0 out of 5
4 Ratings

4 Ratings

S. Hoz ,

Perfect tool for a neurosurgeon!

actually i use all 3 form available of UpSurgeOn app for the last few months, these can sevre the surgeon as a tool for education to demonstrate the topics for colleagues during lectures or any CME event, and also for planning for surgery and to prepare the surgical team for the possible abstacle will be encountered during surgery and even to prepare the needed instruments by the staff, this will improve the orientation of all the surgical team for the target operation and increase the fluency of surgucal steps toward optimizing of surgery, minimizing errors and providing the maximum patient care.


UpSurgeOn S.r.l.
281.6 MB

Requires iOS 7.0 or later. Compatible with iPhone, iPad, and iPod touch.



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  • Family Sharing

    With Family Sharing set up, up to six family members can use this app.

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