Sepsis Clinical Guide 17+

Know sepsis, save lives

Escavo, Inc

Designed for iPad

    • 4.8 • 304 Ratings
    • Free



Version 6.0 introduces the ESCAVO Clinical Community, a forum where clinicians can exchange ideas, ask questions and collaborate on sepsis and other clinical topics.

Sepsis Clinical Guide now includes access the new ESCAVO Clinical Community, a forum where clinicians can exchange ideas, ask questions and collaborate on sepsis and other clinical topics.

Sepsis is a serious systemic infection that can quickly lead to circulatory shock, organ failure and death if inappropriately treated. In 2017, over 2 million people were admitted to US hospitals for sepsis (#1 cause of index admissions) at a total aggregate cost to the US healthcare system of $38.2 billion dollars (#1 most expensive condition), according to an AHRQ report. Over 270,000 people die of sepsis in the US every year, more than from prostate cancer, breast cancer and AIDS combined. Despite its large toll on public health, public awareness of this condition is poor and the quality of treatment is highly variable often due to delayed recognition and treatment.

In sepsis, time is of the essence. Successful treatment hinges on prompt recognition of symptoms, correct antibiotic administration, and hemodynamic stabilization. Lack of appropriate sepsis management knowledge at the bedside leads to delayed symptom recognition, serious complications, medical errors, increased treatment costs, and avoidable morbidity and mortality. For this reason, we created this app to provide busy health professionals with essential management information based on the latest practice guidelines in a format that is easily accessible at the point of care.

The Sepsis app was developed on the ESCAVO mobile publishing platform created specifically for mobile publishing of scientific content. The platform features an intuitive user interface, search, annotation and bookmarking functions, and calculator support. All content is extensively referenced and footnoted where appropriate.

Clinical topics covered in the Sepsis app include:
- Updated with the latest definitions, diagnostic criteria, and management guidelines including the 2016 Sepsis-3 definitions and the latest Surviving Sepsis Campaign (SSC) guidelines
- Epidemiology, risk factors and pathophysiology of sepsis and septic shock
- Common differentials and etiology, guidelines on performing appropriate H&P and workups
- Management of common causes including hospital-acquired pneumonia (HAP), ventilator-acquired pneumonia (VAP) and intra-abdominal infections
- Sepsis management bundles, early goal-directed therapy, hemodynamic management, adjunctive therapies, mechanical ventilation of sepsis-induced ARDS, and other essential management guidelines from the SSC and the American Thoracic Society (ATS)
- Antibiotic therapy including specific guidelines for the treatment of HAP from ATS and the Infectious Diseases Society of America (IDSA)
- Guidance on the prevention, recognition and treatment of Clostridium difficile based on the latest IDSA guidelines
- Information on the diagnosis and management of pediatric and neonatal sepsis including the management of pediatric fever, important differences from adult sepsis, management of sepsis-induced persistent pulmonary hypertension of the newborn (PPHN), empiric antibiotic treatment recommendations for GBS infections, interventions in pediatric septic shock, and other pediatric-specific information
- Important score calculators including the Sequential Organ Failure Assessment (SOFA), quick-SOFA, SIRS, APACHE II, Multiple Organ Dysfunction Score (MODS), the Simplified Acute Physiology Score (SAPS) II, National Early Warning Score (NEWS), the Clinical Pulmonary Infection (CPI) score, the Inferior Vena Cava Collapsibility Index, and others
- Drug administration information for the management of sepsis including antibacterial and antifungal antibiotics, the latest drugs for emerging multi-drug resistant organisms, adrenergic and other vasoactive agents, corticosteroids and diuretics
- Relevant COVID-19 management information

Recommended by:
- The ED Trauma Critical Care Blog (

What’s New

Version 6.0

- Bug fixes and performance enhancements

Ratings and Reviews

4.8 out of 5
304 Ratings

304 Ratings

drbighead ,

Fantastic resource for Emergency Rooms

Rich in content with clear, simple language and an easy to navigate structure. The scientific literature cited is fully up-to-date and defines the latest in care for this deadly and difficult to diagnose condition.

Waleed.mj ,

Best sepsis review ever

One of the best review ever that i ever read
Quick , easy , simple words that every one can understand it
Thank you for making out life easy

Janeska1958 ,

Great resource!

Being an SICU nurse who now coordinates the ICU database do QI measures, this is a great resource for determining if a patient has sepsis vs. septic shock. Thank you for putting it at our fingertips!

App Privacy

The developer, Escavo, Inc, indicated that the app’s privacy practices may include handling of data as described below. For more information, see the developer’s privacy policy.

Data Not Linked to You

The following data may be collected but it is not linked to your identity:

  • Location
  • Usage Data

Privacy practices may vary, for example, based on the features you use or your age. Learn More

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