Action Potential Dynamics
Explore excitable cells
Free · In‑App Purchases
Explore action potentials, neuronal firing, 13 ion channels, cardiac rhythm, synaptic integration, and axon conduction—including disease-related conditions.
Action Potential Dynamics is an interactive simulator for exploring how ions, channels, currents, and membrane voltage work together.
Watch existing Na⁺, K⁺, and Ca²⁺ particles move through membrane channels while the action potential unfolds on a shared timeline. Drag the time cursor to return to any recorded instant and relate particle motion to channel gates, conductance, current, and voltage.
Explore two cell models
• Neuron: a compact 0–10 ms Hodgkin–Huxley action potential
• Ventricular cell: a 0–500 ms Luo–Rudy I action potential with a calcium-supported plateau
Continue through five more labs
• Ion channels: use current clamp or voltage clamp with 13 channel types, adjustable pulse lengths, channel controls, and clearly distinguished g, I, Vcmd, and zero-current traces.
• Neuronal firing characteristics: compare nine representative neuronal responses and five stimulus protocols.
• Cardiac rhythm: follow conduction from the sinus node to the ventricles, then compare normal rhythm with sinus bradycardia, sinus tachycardia, first-degree AV block, and 2:1 second-degree AV block.
• Synaptic integration: connect excitatory and inhibitory conductance (gE and gI) to membrane voltage and firing. Compare normal activity with simplified epilepsy-related increased-excitation and reduced-inhibition conditions.
• Axon conduction: relate each nodal action-potential peak to the axon diagram, inspect a complete waveform, and compare normal conduction with mild or severe focal demyelination. Current leakage, safety factor, subthreshold depolarization, and conduction failure are shown together.
Learn with
• A clear membrane-particle view and channel-gate states
• Membrane voltage, conductance, and current graphs on one time axis
• Equilibrium potentials and channel-opening probabilities
• Slow playback and a movable time cursor
Pro — one-time purchase
• Record conditions and key measurements from all six simulations
• Compare the latest two results and export all records as CSV
• Run advanced Action Potential experiments with conductance controls and presets
• Hold an Ion Channel trace for before-and-after waveform comparison
• Unlock five specialized neuron presets in Neuronal Firing and Ion Channels
Every diagram, graph, and time cursor is driven by the same model time. Disease-related conditions are simplified comparisons designed to explain mechanisms; they do not reproduce an individual patient’s condition.
All simulations run on your device. Action Potential Dynamics is for learning and visualization only. It is not a medical device and is not intended for diagnosis or treatment.
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The developer, Takashi Nakano, indicated that the app’s privacy practices may include handling of data as described below. For more information, see the developer’s privacy policy .
Data Not Collected
The developer does not collect any data from this app.
Accessibility
The developer has not yet indicated which accessibility features this app supports. Learn More
Information
- Seller
- Takashi Nakano
- Size
- 3.9 MB
- Category
- Education
- Compatibility
Requires iOS 17.0 or later.
- iPhone
Requires iOS 17.0 or later. - iPad
Requires iPadOS 17.0 or later. - Mac
Requires macOS 14.0 or later. - Apple Vision
Requires visionOS 1.0 or later.
- iPhone
- Languages
English and 9 more
- English, French, German, Italian, Japanese, Korean, Portuguese, Simplified Chinese, Spanish, Traditional Chinese
- Age Rating
4+
- 4+
- In-App Purchases
Yes
- Pro $7.99
- Copyright
- © 2026 Takashi Nakano
