bug fixes

• Updated 3 IgA nephropathy trials with the latest results — sibeprenlimab (VOYXACT) 24-month data, ravulizumab Phase 3 interim, iptacopan's full FDA approval • Fixed a mismatched MINTAC trial citation and corrected the related KDIGO treatment recommendation • New flashcards for these updates • Minor performance improvements • Key Result now leads each trial card — headline numbers read first • Wide reference tables show a scroll cue so you don't miss columns • Source links now appear only where a verified guideline document exists • Editorial practice summaries are clearly badged as such • Search clears when you switch sections • Corrected several trial reference links

Added 13 new trials with study flashcards — DASH, DASH-Sodium & SSaSS (diet/sodium), ESPRIT & BPROAD (intensive BP targets), PRECISION & RADIANCE II (new antihypertensive approaches), ORIGIN 3 & APPEAR-C3G (glomerular disease), plus the classic Captopril Collaborative Study. Now covering 227 trials total.

Added PISCES Trial Bug fixes

Bug fixes

Added the new 2026 AHA/ACC/ADA/ASN Cardiovascular-Kidney-Metabolic (CKM) Syndrome guideline, with supporting trials (SELECT, STEP, SURMOUNT) Redesigned the AHA/ACC guideline detail view — collapsible sections, at-a-glance recommendation strength, and visual management-pathway diagrams Fixed choppy scrolling on flashcard answers

Expanded quiz content and refreshed reference material across trials and guidelines. Bug fixes and improvements.

• Guideline flashcards expanded to ~100 guidelines (450+ cards), spanning CKD, hypertension, diabetes & CKD, AKI, hyperkalaemia, all glomerular disease topics, transplantation, and dialysis (HD/PD/KRT) • Each card is grounded directly in the guideline's own recommendation text — no generic trivia • Key thresholds and terms are now highlighted in quiz answers for faster review Bug fixes and performance improvements.

Added REGENCY trial (obinutuzumab phase 3 in lupus nephritis, NEJM 2025). Corrected MENTOR trial (cyclosporin duration, missing 12-month data, safety results). Fixed NOBILITY article link.

• All guidelines now share one consistent, chapter-based layout with colour-coded recommendation grades — easier to browse and study. • The navigation bar now hides while you read a chapter and returns when you close it.

Bug fixes

Browse Drugs A–Z — redesigned The alphabet bar has been replaced with tap-to-filter letter chips. Tap a letter to instantly show only drugs starting with that letter; tap All to restore the full list. No more scrolling or flickering. Cleaner navigation When browsing Conditions, Drug Classes, Guidelines, or Saved trials, the header collapses to show only the search bar — giving you more screen space for content. Content updates Drug classes consolidated and reorganised for easier browsing Anaemia section spelling and terminology corrected throughout KDOQI guidelines updated with latest recommendations Bug fixes and polish Fixed a gap below the search bar on compact views Safe area improvements on notched devices General performance and display refinements

Version 1.6 — Expanded UK Kidney Association (UKKA) Guidelines • Every UKKA guideline chapter now has a concise summary and bedside practice points, in one consistent, at-a-glance format. • Updated to the latest UKKA guidance — including the 2025 Anaemia of CKD and Blood Pressure in Dialysis guidelines, and the new (October 2025) Anticoagulation for AF and VTE in Advanced Kidney Disease guidelines. • Refreshed Hyperkalaemia, AKI, vascular access and kidney biopsy chapters. • Accuracy and content improvements throughout. Thank you for using Landmark Renal Trials. Feedback is always welcome.

Bug fixes and performance improvements.

• 15 new trials added — including Vascular Access, MRA & Novel Agents, and emerging complement/SGLT2 trials (VALIANT, VISIONARY, EASi-KIDNEY, ZENITH-CKD and more) • 3 new guideline organisations — KDOQI, ABCD (Diabetes & CKD), and BTS/Transplant • Trials now open with smooth animation and collapse others automatically • Navigation bar clears when reading a trial or guideline for a full-screen view • Back button added on Trials and Guidelines sections • Settings panel now closes when tapping anywhere outside • Layout and scrolling fixes on desktop

1. Improved timeline readability with larger category labels 2. Timeline category column now stays fixed while scrolling 3. Minor display improvements

• Compare trials side-by-side to spot key differences at a glance • Emerging Trials section — browse Phase 2–3 trials shaping the future of nephrology • Guideline cross-links on trial cards — tap to jump directly to related KDIGO, UKKA, ISPD and other guidelines • Improved search with keyboard navigation support • Bug fixes and performance improvements

Trial Comparison Select 2–3 trials and compare them side by side — population, intervention, primary endpoint, key result, and guideline impact in a single table. Key Stats on Every Card Landmark trials now display NNT, HR, and ARR as colour-coded badges directly on the card — green for NNT, blue for HR, amber for ARR — so the numbers that matter at the bedside are always visible. Share a Trial Tap Share in any expanded trial card to send the trial name, finding, and guideline impact via iMessage, email, or any app on your phone. Smarter Search Search now understands medical synonyms — searching "dialysis adequacy" finds Kt/V content, "SGLT2" finds DAPA-CKD and CREDENCE, "anaemia" finds ESA trials. Includes autocomplete and tolerance for typos. Visual Evidence Timeline A new swim-lane timeline shows all trials plotted by year, grouped by category — scroll horizontally through 35+ years of nephrology evidence. Saved Library Bookmark any trial or guideline and find them instantly in your personal Saved Library from the home screen. Guideline Cross-References Tap any trial name mentioned in a guideline card to open that trial's full detail without leaving the page.