NeuroPhysMatrix
Explore neuronal physiology
Free · In‑App Purchases
Explore neurons by changing stimuli, channels, synaptic inputs, and circuit connections. Compare six simulations with linked graphs, diagrams, and guides.
NeuroPhysMatrix lets you explore neuronal action potentials, firing characteristics, ion channels, synaptic integration, neural circuits, and axon conduction by changing simulation parameters.
Change stimulus strength and duration, channel conductance, input location, and connection strength to see how membrane voltage and currents respond.
SIX SIMULATIONS
• Action Potential: Relate membrane voltage to Na⁺ and K⁺ currents, channel states, and ion movement. Explore refractoriness with paired stimuli, strength–duration curves, and recovery from Na⁺ inactivation.
• Neuronal Firing Characteristics: Compare firing rate, adaptation, delayed firing, and rebound responses in representative neuron models.
• Ion Channels: Use current clamp and voltage clamp to explore the relationship between membrane voltage and 14 representative channels and background currents.
• Synaptic Integration: Compare how input location, number, strength, timing, and dendritic morphology affect voltage responses.
• Neural Circuits: Change excitatory and inhibitory connection strengths and transmission delays. Observe interactions through voltage traces and spike rasters.
• Axon Conduction: Explore schematic models of myelinated and unmyelinated conduction and the effects of focal demyelination.
KEEP RESULTS IN VIEW
Change the time-axis range and observation time to connect waveforms with diagrams. Switch between Settings and Guide to review parameter meanings and key points while exploring results.
PRO — ONE-TIME PURCHASE
• Edit cell count, wiring, and the stimulated cell in neural circuits.
• Edit dendritic branches, parent connections, length, and diameter.
• Save and load custom circuits or dendrites together with their input conditions.
• Record experiment conditions and key measurements, compare numerical results, and export CSV.
• Adjust action-potential conductances and use comparison features.
• Hold ion-channel and dendritic traces to compare responses before and after changes.
• Unlock five specialized neuron presets.
Basic simulations, circuit and dendritic morphology presets, basic settings, and guides are free. Four foundational neuron presets are free; five additional presets are included in Pro.
Available on iPhone, iPad, and Mac in 10 languages.
Waveforms and diagrams are computational models and schematic representations, not exact reproductions of a particular biological cell or patient. This app is not a medical device and is not intended for diagnosis or treatment.
Ratings & Reviews
- This app hasn’t received enough ratings or reviews to display an overview.
The app is now called NeuroPhysMatrix, with more ways to explore and experiment with neuronal electrophysiology.
• Added neural-circuit simulations for excitatory chains, feedforward inhibition, recurrent inhibition, and disinhibition.
• Combined synaptic inputs and dendritic integration in one workspace and added representative neuronal morphology presets.
• Added direct click, tap, and drag editing of circuits and dendrites, plus saving and loading of custom configurations (Pro).
• Added action-potential experiments for paired-stimulus refractoriness, strength–duration curves, and recovery from Na⁺ inactivation.
• Added SK current to Ion Channels, bringing the selection to 14 representative channels and background currents.
• Added adjustable time-axis ranges in each simulation.
• Unified Settings and Guide layouts, making it easier to keep results visible on iPhone, iPad, and Mac.
• Improved graphs, model explanations, experiment records, and usability.
We have reorganized the content to focus on neuronal simulations.
Existing Pro customers can use the newly added Pro features without an additional purchase.
The developer, Takashi Nakano, indicated that the app’s privacy practices may include handling of data as described below. For more information, see the developer’s privacy policy .
Data Not Collected
The developer does not collect any data from this app.
Accessibility
The developer has not yet indicated which accessibility features this app supports. Learn More
Information
- Seller
- Takashi Nakano
- Size
- 5 MB
- Category
- Education
- Compatibility
Requires iOS 17.0 or later.
- iPhone
Requires iOS 17.0 or later. - iPad
Requires iPadOS 17.0 or later. - Mac
Requires macOS 14.0 or later. - Apple Vision
Requires visionOS 1.0 or later.
- iPhone
- Languages
English and 9 more
- English, French, German, Italian, Japanese, Korean, Portuguese, Simplified Chinese, Spanish, Traditional Chinese
- Age Rating
4+
- 4+
- In-App Purchases
Yes
- Pro $7.99
- Copyright
- © 2026 Takashi Nakano
