PathoPlay Pathophysiology Game

Disease Mechanisms Made Simple

Free · In‑App Purchases · Designed for iPad. Not verified for macOS.

Dive into clinical puzzles that transform complex disease pathways into step-by-step mechanisms you actually remember. 550 interactive puzzles across 10 body systems. PathoPlay is a pathophysiology and pharmacology puzzle game that teaches you how diseases work and how drugs treat them - not by memorizing facts, but by tracing the mechanism from trigger to clinical outcome, then blocking the pathway with the right drug. Can you connect the chain? Portal hypertension → increased splanchnic capillary pressure → fluid transudation → ascites. Every link matters. Miss one, and the pathway breaks. Now can you treat it? A disease pathway is active. Five drugs sit in your cart. Only one hits the right molecular target. Choose wrong, and the cascade continues. HOW IT WORKS • Mechanism Chains - Drag and connect steps from trigger to clinical outcome. Understand why each step causes the next. • Reverse Mode - Start with a clinical finding and trace backwards to the root cause. • Versus Mode - Two similar diseases side by side. Fill in the gaps to learn what makes them different. • Treat Mode - A disease pathway is active. Drag the correct drug onto the right molecular target to block the cascade. Learn pharmacology by mechanism, not memorization. • Daily Challenge - One new chain every day. Build your streak in under 3 minutes. 550 PUZZLES ACROSS 10 BODY SYSTEMS Pathophysiology chains AND pharmacology puzzles in every system: • Cardiovascular - Heart failure, ACS, shock, arrhythmias, hypertension. • Respiratory - COPD, asthma, pulmonary embolism, ARDS, cystic fibrosis. • Renal - AKI, CKD, nephrotic vs nephritic, electrolyte disorders. • GI & Hepatology - Cirrhosis, peptic ulcer, GI bleeding, hepatitis C. • Neurology - Stroke, seizures, Parkinson's, depression, myasthenia gravis. • Endocrine - DKA, thyroid storm, adrenal insufficiency, acromegaly. • Infectious Disease - TB, HIV, MRSA, fungal meningitis, PCP. • Hematology - Anemias, HIT, CML, hemophilia, sickle cell disease. • Reproductive - Preeclampsia, PCOS, breast cancer, PPH. • Rheumatology - Gout, RA, SLE, vasculitis, MAS. WHO IS PATHOPLAY FOR • Medical students preparing for USMLE and pathophysiology exams. • Nursing students mastering disease mechanisms for NCLEX. • PA, NP, and pharmacy students building clinical reasoning foundations. • Anyone who wants to understand why diseases happen and how drugs work. WHY PATHOPLAY WORKS Most study tools ask you to recall facts. PathoPlay asks you to think. By building mechanism chains and blocking them with the right drug, you develop deep understanding that survives exam pressure and translates to real clinical reasoning. Every completed chain ends with a clinical pearl referenced to standard medical textbooks. From the makers of MedDiagnosis - the clinical case simulator trusted by medical students worldwide. PathoPlay builds the foundation. MedDiagnosis puts it into practice. SIMPLE ACCESS • 200 pathophysiology chains free across all 10 body systems • One-time purchase unlocks Reverse, Versus, Treat and all future content • No subscriptions • No ads • Fully offline Support: contact@diagnosticstudios.com | www.diagnosticstudios.com Evidence-based content referenced to Robbins & Cotran, Harrison's, Guyton & Hall, Goodman & Gilman's, and Pathoma. Educational use only. Not for clinical decision-making. USMLE® is a trademark of NBME/FSMB. No affiliation or endorsement.

Ratings & Reviews

  • This app hasn’t received enough ratings or reviews to display an overview.

Bug Fixes & Improvements - Results screen now scrolls properly on smaller devices - Daily Challenge status now updates correctly across days - Drug card order is randomized in Treat mode

Version 1.2.2

The developer, Helena Kaso, indicated that the app’s privacy practices may include handling of data as described below. For more information, see the developer’s privacy policy .

  • Data Not Linked to You

    The following data may be collected but it is not linked to your identity:

    • Identifiers
    • Usage Data
    • Diagnostics

Privacy practices may vary, for example, based on the features you use or your age. Learn More

Accessibility

The developer has not yet indicated which accessibility features this app supports. Learn More

Information

Seller
  • Helena Kaso
Size
  • 59.8 MB
Category
  • Medical
Compatibility
Requires iOS 15.1 or later.
  • iPhone
    Requires iOS 15.1 or later.
  • iPad
    Requires iPadOS 15.1 or later.
  • iPod touch
    Requires iOS 15.1 or later.
  • Mac
    Requires macOS 12.0 or later and a Mac with Apple M1 chip or later.
  • Apple Vision
    Requires visionOS 1.0 or later.
Languages
  • English
Age Rating
16+
In-App Purchases
Yes
Copyright
  • © 2026 Diagnostic Studios
  • Developer Website
  • Privacy Policy

    • More by Helena Kaso