We’ve refreshed the layout and expanded the guides to help you choose an experiment by what you want to learn and understand both its controls and results. • Added a home page introducing all seven experiments and their learning goals. Open each experiment or its guide directly from its card. • Expanded the guides in all 10 languages, with detailed explanations of learning goals, model principles, settings, graphs and numerical values. • Added free three-step tutorials: observe a baseline, change one condition and compare the results. Return to the home page and continue your current tutorial. • Added “Curves & legend” to “Action potential” and “Ion channels”, making it easier to show or hide curves from a list. • Improved layouts for iPhone, iPad and iPhone Duo across screen sizes and orientations. Graphs and controls are easier to read on small screens and with larger text. • Added save feedback, comparison guidance and confirmation before deletion in Experiment Log (Pro). Improved CSV export error messages.

An optogenetics simulation has been added to celebrate the 2026 Nobel Prize in Physiology or Medicine. • Unified preset selection, saving, loading and reset controls across all seven workspaces. • Protected existing experiment records at the 50-record limit and prevented recording before calculation finishes. • Clarified gate values, time labels and Pro feature descriptions. The app is now called NeuroPhysMatrix, with more ways to explore and experiment with neuronal electrophysiology. • Added neural-circuit simulations for excitatory chains, feedforward inhibition, recurrent inhibition, and disinhibition. • Combined synaptic inputs and dendritic integration in one workspace and added representative neuronal morphology presets. • Added direct click, tap, and drag editing of circuits and dendrites, plus saving and loading of custom configurations (Pro). • Added action-potential experiments for paired-stimulus refractoriness, strength–duration curves, and recovery from Na⁺ inactivation. • Added SK current to Ion Channels, bringing the selection to 14 representative channels and background currents. • Added adjustable time-axis ranges in each simulation. • Unified Settings and Guide layouts, making it easier to keep results visible on iPhone, iPad, and Mac. • Improved graphs, model explanations, experiment records, and usability. We have reorganized the content to focus on neuronal simulations. Existing Pro customers can use the newly added Pro features without an additional purchase.

The app is now called NeuroPhysMatrix, with more ways to explore and experiment with neuronal electrophysiology. • Added neural-circuit simulations for excitatory chains, feedforward inhibition, recurrent inhibition, and disinhibition. • Combined synaptic inputs and dendritic integration in one workspace and added representative neuronal morphology presets. • Added direct click, tap, and drag editing of circuits and dendrites, plus saving and loading of custom configurations (Pro). • Added action-potential experiments for paired-stimulus refractoriness, strength–duration curves, and recovery from Na⁺ inactivation. • Added SK current to Ion Channels, bringing the selection to 14 representative channels and background currents. • Added adjustable time-axis ranges in each simulation. • Unified Settings and Guide layouts, making it easier to keep results visible on iPhone, iPad, and Mac. • Improved graphs, model explanations, experiment records, and usability. We have reorganized the content to focus on neuronal simulations. Existing Pro customers can use the newly added Pro features without an additional purchase.