• New level types, each marked on the map: Antibiogram (read the lab's report and name the enzyme), Drug cards (hold two or three drugs and swap to the right one), Narrow it and Switch it. • The Lab is unlocked from the start • The Book's Show all switch shows every drug and bug, not only the ones you've met. • Today shows two leaderboards: all time on top, today's below.

• Today's shift has its own page: see today's top three before your shift, and your best run, rank and Share after it. Play again is practice. • Cell wall Siege: every round now asks only what the cell wall lesson teaches. • Build the Slide: the line under each bug now tells you to build its slide from memory.

• Night Shift leaderboards: Finish Today's shift and see your rank, challenge your colleagues • Culture results: in some levels the culture comes back while you play, and you choose the drug to narrow to. • Antibiogram levels: read the antibiogram, name the resistance enzyme, then narrow the therapy. • Leave the map alone for a moment and see what your bug gets up to.

• Night Shift leaderboards: play Today's shift and see how your score compares with other players in Game Center. Everyone gets the same plate each day, and a second leaderboard keeps the best scores of all time. • Quick tour: a short walk through the game for new players. • Culture results: in some levels the culture result comes back while you play, and you choose the drug to narrow to. • Antibiogram levels: read the antibiogram, name the resistance enzyme, then narrow the therapy. • Two new lessons: β-lactamases, and CRAB with sulbactam-durlobactam. • A clearer Study: one numbered path for each drug target, with rings that fill as you go. You can also revise by pathogen or by infection. • A new walk-through for fosfomycin. • A calmer look with flat tiles and clearer bug names, content corrections.

- New: a short Quick tour for first-time players, which you can skip. - New: the Cystitis drugs walk-through, on fosfomycin, nitrofurantoin and pivmecillinam. - Fixes in the Cell wall lesson and on the map. Thank you for every report and review!

• Animated lessons: watch how antibiotics work, step by step. The cell wall, the ribosome, DNA gyrase, metronidazole, nitrofurantoin, folate synthesis and the cell membrane (daptomycin). • Animated resistance lessons: MRSA, enterococci and VRE, ESBL and AmpC, carbapenemases and CRAB, and cefiderocol. • Each lesson ends with a short quiz, and a quick check lets you skip what you already know. • Every drug class gets a step-by-step walk-through. • The map now follows drug classes, in the same order as Study. • Night Shift: a new daily board with a score to beat. • The Lab: build a Gram stain slide and train your eye at the microscope. • New bugs: Strep B, S. epidermidis and Citrobacter. • Spot a mistake? Tap the flag at the top of a page to report it. • Your progress is now kept more safely on your phone. • Many fixes, clearer texts and a calmer look.