You can now explore the AMP feature and 3D structure prediction freely, and will only be prompted to upgrade when you choose to proceed with peptide sequence analysis.

Added support for in-app purchases.

Added a clearer warning message when the anti-microbial spectrum cannot be retrieved.

Added a function to assess the likelihood of antimicrobial activity spectrum for a user-provided peptide.

1. Added a Paste button to quickly insert a copied sequence into the peptide input field. 2. Added a 2D button to display Chou-Fasman 2D structure predictions for your peptide.

Amino Acid Propensities around the central one-letter amino acid code show secondary structure likelihoods in colour for a cleaner, more visually appealing display in light and dark modes.

Each amino acid in the input table shows its secondary structure propensities: α (alpha-helix), β (beta-sheet), τ (turn), and ε (coil), helping users design peptides more intuitively.

Animated codon optimisation process showing random intermediate sequences with smooth, peptide length-adaptive animations and bold red highlights, leading up to the final optimized sequence.

Added a seed input field to control random codon generation, allowing users to reproduce or explore different codon sequences by adjusting the seed value.

The new Moderate Expression mode selects codons multinomially by natural frequency to create balanced, stable, and less repetitive DNA sequences.

Improved user guidance with confirmation prompts before clearing entered sequences or launching external searches and structure predictions.

Peptide sequences are now uploaded and processed more securely, with improved privacy and cleaner URLs during 3D structure prediction.

Added an option for reverse translation from peptide to DNA to optimize expression in E. coli, yeast, and human.

Added a button to upload peptide sequences to GitHub Gist and load them in the AlphaFold Colab notebook using the user’s Google account, enabling seamless input and effortless 3D structure prediction. Data is processed securely within the user’s own Google Colab environment.

1. Added three new indices (Boman Index, Flexibility, and Polarizability) to the peptide profile table. 2. Redesigned the layout and appearance of the table and chart for a more intuitive and streamlined experience. 3. Implemented a save button for peptide profiles.

1. Visualized amino acid composition with color-coded grouping. 2. Added titration curve for the peptide sequence 3. Included peptide half-life estimation based on composition

1. Implemented direct "Clear Sequence" and "C-terminal Deletion" buttons within the 2D amino acid property table for improved ease of use. 2. Added functionality to calculate the hydrophobic moment of peptide sequences and visualize the helical wheel model with customizable residue angles.